Program

9h-9h30: OPENING SESSION

9h30-10h45: DIAGNOSTIC

José Flávio Videira / Rosália Costa / Elisabete Rios

Pitfalls in the diagnostic biopsy (Davide Gigliano)

How to stratify disease after neoadjuvant approach (Andre Coelho)

Is there any situation that radiologic exams can "replace" biopsy? (Pedro Martins)

Hereditary and GIST: when to suspect (Rita Quental)

10h45-11h05: BREAK

11h05-12h10: EARLY STAGE DISEASE

Jorge Guimarães dos Santos / António Moreira / Alexandre Sousa

Patients eligible only for surveillance (Diana Freitas)

Surgery: radicality according to location (Marco Fiore)

Adjuvant imatinib treatment: for whom, what dose and for how long? (Ana Ferreira)

12h10-12h50: THINKING ABOUT MECHANISMS OF ACTION AND RESISTANCE

Júlia Amorim / Ana Peixoto

A different multi kinase inhibitor: ripretinib (Joana Mendonça)

What we already know about mechanisms of resistance and the role of ctDNA (Cesar Serrano)

12h50-14h15: LUNCH

14h15-15h15: ADVANCED DISEASE

Nuno Abecassis / Lúcia Águas / Miguel Abreu

The role of surgery in first relapse and in subsequent progressions (José António Gonzalez)

Mutational status' implications in relapse approach (Maria Cassiano)

Is there a place for imatinib 800mg in the era of new TKIs? (Cecilia Melo Alvim )

15h15-15h50: FUTURE PERSPECTIVES

Helder Mansinho / Filomena Pina / Andreia Costa

New strategies of systemic treatment in advanced disease (Claudia Valverde)

Are there new places for radiotherapy? (Artur Aguiar)

15h50-16h10: BREAK

16h10-17h20: APPROACH OF RARE FORMS

Anabela Barros / Mariana Afonso / Rui Caetano Oliveira

SDH deficient GIST (Daniela Almeida)

GIST with 842V PDGFRA mutation (Cesar Serrano)

Quadruple negative GIST (Javier M. Broto)

17h20-17h50: DISCUSSION OF INTERACTIVE CLINICAL CASES

Hugo Vasques / Nuno Bonito / António Silva

Case 1: Life threatening GIST (discussing situation recognition and approach) (Catarina Baia)

Case 2: Long responders (discussing the characteristics of these patients,
radiologic surveillance, possibility to stop treatment) (Michelle Silva)

18h: CLOSE SESSION